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1

Analysis of the immunoglobulin G (IgG) secretion efficiency in recombinant Chinese hamster ovary (CHO) cells by using Citrine-fusion IgG

Kaneyoshi, Kohei, Yamano-Adachi, Noriko, Koga, Yuichi, Uchiyama, Keiji, Omasa, Takeshi

Journal:

Year:

2019

Language:

english

File:

PDF, 2.31 MB

english, 2019

2

Secretion analysis of intracellular “difficult-to-express” immunoglobulin G (IgG) in Chinese hamster ovary (CHO) cells

Kaneyoshi, Kohei, Kuroda, Kouki, Uchiyama, Keiji, Onitsuka, Masayoshi, Yamano-Adachi, Noriko, Koga, Yuichi, Omasa, Takeshi

Journal:

Year:

2019

Language:

english

File:

PDF, 1.61 MB

english, 2019

3

Synthetic metabolic engineering-a novel, simple technology for designing a chimeric metabolic pathway

Ye, Xiaoting, Honda, Kohsuke, Sakai, Takaaki, Okano, Kenji, Omasa, Takeshi, Hirota, Ryuichi, Kuroda, Akio, Ohtake, Hisao

Journal:

Microbial Cell Factories

Year:

2012

Language:

english

File:

PDF, 252 KB

english, 2012

4

Systematic screening ofEscherichia colisingle-gene knockout mutants for improving recombinant whole-cell biocatalysts

Ying Zhou, Takeshi Minami, Kohsuke Honda, Takeshi Omasa, Hisao Ohtake

Journal:

Applied Microbiology and Biotechnology

Year:

2010

Language:

english

File:

PDF, 225 KB

english, 2010

5

Constrained optimization of l-lysine production based on metabolic flux using a mathematical programming method

Kiyoshi Tada, Michimasa Kishimoto, Takeshi Omasa, Yoshio Katakura, Ken-Ichi Suga

Journal:

Journal of Bioscience and Bioengineering

Year:

2001

Language:

english

File:

PDF, 589 KB

english, 2001

6

Inhibition of CYP3A4 by 6′,7′-dihydroxybergamottin in human CYP3A4 over-expressed hepG2 cells

Nobutaka Araki, Shuichi Tsuruoka, Gohki Hasegawa, Hayato Yanagihara, Takeshi Omasa, Shin Enosawa, Yasushi Yamazoe, Akio Fujimura

Journal:

Journal of Pharmacy and Pharmacology

Year:

2012

Language:

english

File:

PDF, 514 KB

english, 2012

7

The osteoblastic differentiation ability of human dedifferentiated fat cells is higher than that of adipose stem cells from the buccal fat pad

Kishimoto, Naotaka, Momota, Yoshihiro, Hashimoto, Yoshiya, Tatsumi, Shinichi, Ando, Kayoko, Omasa, Takeshi, Kotani, Junichiro

Journal:

Clinical Oral Investigations

Year:

2014

Language:

english

File:

PDF, 1.00 MB

english, 2014

8

Optimization of cell line development in the GS-CHO expression system using a high-throughput, single cell-based clone selection system

Nakamura, Tsuyoshi, Omasa, Takeshi

Journal:

Journal of Bioscience and Bioengineering

Year:

2015

Language:

english

File:

PDF, 1.05 MB

english, 2015

9

Cell Engineering and Cultivation of Chinese Hamster Ovary (CHO) Cells

Omasa, Takeshi, Onitsuka, Masayoshi, Kim, Wook-Dong

Journal:

Current Pharmaceutical Biotechnology

Year:

2010

Language:

english

File:

PDF, 403 KB

english, 2010

10

The Difference in Sterility due to High Temperatures during the Flowering Period among Japonica-Rice Varieties.

Matsui, Tsutomu, Omasa, Kenji, Horie, Takeshi

Journal:

Plant Production Science

Year:

2001

Language:

english

File:

PDF, 3.04 MB

english, 2001

11

Improved recombinant antibody production by CHO cells using a production enhancer DNA element with repeated transgene integration at a predetermined chromosomal site

Kawabe, Yoshinori, Inao, Takanori, Komatsu, Shodai, Huang, Guan, Ito, Akira, Omasa, Takeshi, Kamihira, Masamichi

Journal:

Journal of Bioscience and Bioengineering

Year:

2016

Language:

english

File:

PDF, 1.90 MB

english, 2016

12

Force Visualization Mechanism using Moire Fringe for Endoscopic Surgical Instruments

Takaki, Takeshi, Omasa, Youhei, Ishii, Idaku, Kawahara, Tomohiro, Sumitani, Daisuke, Yoshida, Makoto, Okajima, Masazumi

Journal:

Journal of Japan Society of Computer Aided Surgery

Year:

2009

File:

PDF, 9.63 MB

2009

13

Analysis of intracellular IgG secretion in Chinese hamster ovary cells to improve IgG production

Kaneyoshi, Kohei, Uchiyama, Keiji, Onitsuka, Masayoshi, Yamano, Noriko, Koga, Yuichi, Omasa, Takeshi

Journal:

Journal of Bioscience and Bioengineering

Year:

2018

Language:

english

File:

PDF, 1.43 MB

english, 2018

14

EGCG improves recombinant protein productivity in Chinese hamster ovary cell cultures via cell proliferation control

Yamano, Noriko, Omasa, Takeshi

Journal:

Year:

2018

Language:

english

File:

PDF, 645 KB

english, 2018

15

Secretory leakage of IgG1 aggregates from recombinant Chinese hamster ovary cells

Onitsuka, Masayoshi, Kadoya, Yukinori, Omasa, Takeshi

Journal:

Journal of Bioscience and Bioengineering

Year:

2018

Language:

english

File:

PDF, 1.04 MB

english, 2018

16

Flow cytometry: An improved method for the selection of highly productive gene-amplified CHO cells using flow cytometry

Tomohiro Yoshikawa, Fumi Nakanishi, Yuki Ogura, Daisuke Oi, Takeshi Omasa, Yoshio Katakura, Michimasa Kishimoto, Ken-Ichi Suga

Journal:

Biotechnology and Bioengineering

Year:

2001

Language:

english

File:

PDF, 216 KB

english, 2001

17

Improved production of recombinant human antithrombin III in Chinese hamster ovary cells by ATF4 overexpression

Tomoshi Ohya, Tetsuji Hayashi, Eriko Kiyama, Hiroko Nishii, Hideo Miki, Kaoru Kobayashi, Kohsuke Honda, Takeshi Omasa, Hisao Ohtake

Journal:

Biotechnology and Bioengineering

Year:

2008

Language:

english

File:

PDF, 260 KB

english, 2008

18

Bacterial artificial chromosome library for genome-wide analysis of Chinese hamster ovary cells

Takeshi Omasa, Yihua Cao, Joon Young Park, Yasuhiro Takagi, Shuichi Kimura, Hidenori Yano, Kohsuke Honda, Shuichi Asakawa, Nobuyoshi Shimizu, Hisao Ohtake

Journal:

Biotechnology and Bioengineering

Year:

2009

Language:

english

File:

PDF, 866 KB

english, 2009

19

Effects of lactate concentration on hybridoma culture in lactate-controlled fed-batch operation

Takeshi Omasa, Ken-Ichi Higashiyama, Suteaki Shioya, Ken-ichi Suga

Journal:

Biotechnology and Bioengineering

Year:

1992

Language:

english

File:

PDF, 776 KB

english, 1992

20

Enhancement of antibody production by growth factor addition in perfusion and hollow-fiber culture systems

Takeshi Omasa, Masaki Kobayashi, Toshio Nishikawa, Suteaki Shioya, Ken-ichi Suga, Syo-ichi Uemura, Yasuo Kitani, Yoshio Imamura

Journal:

Biotechnology and Bioengineering

Year:

1995

Language:

english

File:

PDF, 655 KB

english, 1995

21

Low-intensity laser irradiation stimulates mineralization via increased BMPs in MC3T3-E1 cells

Keiko Fujimoto, Takeshi Kiyosaki, Narihiro Mitsui, Kotoe Mayahara, Saori Omasa, Naoto Suzuki, Noriyoshi Shimizu

Journal:

Lasers in Surgery and Medicine

Year:

2010

Language:

english

File:

PDF, 260 KB

english, 2010

22

Lipids and fatty acids in guard-cell protoplasts from Vicia faba leaves

Takeshi Sakaki, Atushi Satoh, Kiyoshi Tanaka, Kenji Omasa, Ken-Ichiro Shimazaki

Journal:

Year:

1995

Language:

english

File:

PDF, 520 KB

english, 1995

23

Expression and amplification of glutamine synthetase gene endows HepG2 cells with ammonia-metabolizing activity for bioartificial liver support system

Takeshi Omasa, Mitsugu Yamanaka, Naoko Tanimura, Yoshio Katakura, Michimasa Kishimoto, Ken-ichi Suga, Shin Enosawa

Journal:

Enzyme and Microbial Technology

Year:

2004

Language:

english

File:

PDF, 154 KB

english, 2004

24

An attempt at decision making in tissue engineering: reactor evaluation using the analytic hierarchy process (AHP)

Takeshi Omasa, Michimasa Kishimoto, Masaya Kawase, Kiyohito Yagi

Journal:

Biochemical Engineering Journal

Year:

2004

Language:

english

File:

PDF, 163 KB

english, 2004

25

Extractive lactic acid fermentation with tri-n-decylamine as the extractant

Min-Tian Gao, Takashi Shimamura, Nobuhiro Ishida, Eiji Nagamori, Haruo Takahashi, Shinji Umemoto, Takeshi Omasa, Hisao Ohtake

Journal:

Enzyme and Microbial Technology

Year:

2009

Language:

english

File:

PDF, 442 KB

english, 2009

26

Production of 2-deoxyribose 5-phosphate from fructose to demonstrate a potential of artificial bio-synthetic pathway using thermophilic enzymes

Kohsuke Honda, Shohei Maya, Takeshi Omasa, Ryuichi Hirota, Akio Kuroda, Hisao Ohtake

Journal:

Journal of Biotechnology

Year:

2010

Language:

english

File:

PDF, 197 KB

english, 2010

27

Effects of palindrome structure on Dhfr amplification in Chinese hamster ovary cells

Joon Young Park, Miyuki Yamatani, Souhei Wadano, Yasuhiro Takagi, Kohsuke Honda, Takeshi Omasa, Hisao Ohtake

Journal:

Process Biochemistry

Year:

2010

Language:

english

File:

PDF, 961 KB

english, 2010

28

Simultaneous thermogravimetry and differential thermal analysis for comparing burning characteristics between oleaginous and non-oleaginous microorganisms

Bongmun Kang, Kohsuke Honda, Tsunehiro Aki, Takeshi Omasa, Hisao Ohtake

Journal:

Thermochimica Acta

Year:

2011

Language:

english

File:

PDF, 601 KB

english, 2011

29

“Biochemical Engineering Science” dedicated to Professor Dr. T. Yoshida

Takeshi Omasa, Jian-Jiang Zhong

Journal:

Process Biochemistry

Year:

2010

Language:

english

File:

PDF, 164 KB

english, 2010

30

Efficient production of desulfurizing cells with the aid of expert system

Michimasa Kishimoto, Masaaki Inui, Takeshi Omasa, Yoshio Katakura, Ken-ichi Suga, Koichi Okumura

Journal:

Biochemical Engineering Journal

Year:

2000

Language:

english

File:

PDF, 234 KB

english, 2000

31

Artificial Mimicking of Physiological Active Transport by a Membrane Co-cultured with Two Different Cells: Hepatic Origin HepG2 and Renal Origin PCTL-MDR

Mitsufumi Endo, Shin Enosawa, Michitaka Ozaki, Shuichi Tsuruoka, Shinya Hiramatsu, Kazumi Kim, Takeshi Omasa, Toshiharu Matsumura, Tatsuya Aoki, Yasuhisa Koyanagi, Seiichi Suzuki

Journal:

Artificial Organs

Year:

2002

Language:

english

File:

PDF, 162 KB

english, 2002

32

ATF4 over-expression increased IgG1productivity in Chinese hamster ovary cells

Ahmad M Haredy, Akitoshi Nishizawa, Kohsuke Honda, Tomoshi Ohya, Hisao Ohtake, Takeshi Omasa

Journal:

BMC Proceedings

Year:

2011

Language:

english

File:

PDF, 94 KB

english, 2011

33

Chromosome identification and its application in Chinese hamster ovary cells

Yihua Cao, Shuichi Kimura, Joon-young Park, Miyuki Yamatani, Kohsuke Honda, Hisao Ohtake, Takeshi Omasa

Journal:

BMC Proceedings

Year:

2011

Language:

english

File:

PDF, 293 KB

english, 2011

34

Real time monitoring of drug metabolic enzyme response inside human hepatoma GS-3A4-HepG2 cells by means of electrochemical impedance measurement

Masaaki Kobayashi, Nobuhiro Sugihara, Hirohiko Ise, Takeshi Omasa, Naoki Negishi

Journal:

Polymers for Advanced Technologies

Year:

2004

Language:

english

File:

PDF, 332 KB

english, 2004

35

Recognition of culture state using two-dimensional gel electrophoresis with an artificial neural network

Naoki Izawa, Michimasa Kishimoto, Masaaki Konishi, Takeshi Omasa, Suteaki Shioya, Hisao Ohtake

Journal:

Year:

2006

Language:

english

File:

PDF, 429 KB

english, 2006

36

Enhancement effects of BSA and linoleic acid on hybridoma cell growth and antibody production

Masaki Kobayashi, Satoru Kato, Takeshi Omasa, Suteaki Shioya, Ken-ichi Suga

Journal:

Year:

1994

Language:

english

File:

PDF, 529 KB

english, 1994

37

Application of circulatory flow bioreactor for long-term and large-scale culture of glutamine synthetase transduced CHO cells and its ammonia removal activity with an aim of development for a bioartificial liver assist system

Shin Enosawa, Toshiyuki Mukaiyama, Tomoyuki Miyashita, Xiao-Kang Li, Seiichi Suzuki, Hiroshi Amemiya, Toshiharu Matsumura, Takeshi Omasa, Kenichi Suga

Journal:

Journal of Artificial Organs

Year:

2001

Language:

english

File:

PDF, 577 KB

english, 2001

38

Coculture of hepatic and renal origin cell lines provides biohemofiltration with an active transport system of xenobiotics metabolites

Mitsufumi Endo, Shin Enosawa, Seiichi Suzuki, Hiroshi Amemiya, Shuichi Tsuruoka, Akio Fujimura, Shinya Hiramatsu, Takeshi Omasa, Kenichi Suga, Toshiharu Matsumura, Tatsuya Aoki, Yasuhisa Koyanagi

Journal:

Journal of Artificial Organs

Year:

2001

Language:

english

File:

PDF, 1004 KB

english, 2001

39

A bioreactor with glutamine synthetase-transfected recombinant HepG2 cells exhibits ammonia removal activity without the need for added cofactors and substrates: Advantage of a cellular bioreactor over enzyme-immobilized beads

Shin Enosawa, Tomoyuki Miyashita, Xiao-Kang Li, Seiichi Suzuki, Hiroshi Amemiya, Takeshi Omasa, Kenichi Suga, Toshiharu Matsumura

Journal:

Journal of Artificial Organs

Year:

2001

Language:

english

File:

PDF, 533 KB

english, 2001

40

The enhancement of specific antibody production rate in glucose- and glutamine-controlled fed-batch culture

Takeshi Omasa, Masaru Ishimoto, Ken-ichi Higashiyama, Suteaki Shioya, Ken-ichi Suga

Journal:

Year:

1992

Language:

english

File:

PDF, 625 KB

english, 1992

41

Utilization of hydrophobic bacteriumRhodococcus opacusB-4 as whole-cell catalyst in anhydrous organic solvents

Shiho Yamashita, Masafumi Satoi, Yoshihiro Iwasa, Kohsuke Honda, Yuka Sameshima, Takeshi Omasa, Junichi Kato, Hisao Ohtake

Journal:

Applied Microbiology and Biotechnology

Year:

2007

Language:

english

File:

PDF, 197 KB

english, 2007

42

Stabilization of water-in-oil emulsion byRhodococcus opacusB-4 and its application to biotransformation

Kohsuke Honda, Shiho Yamashita, Hiroyuki Nakagawa, Yuka Sameshima, Takeshi Omasa, Junichi Kato, Hisao Ohtake

Journal:

Applied Microbiology and Biotechnology

Year:

2008

Language:

english

File:

PDF, 259 KB

english, 2008

43

Glycosylation pattern of humanized IgG-like bispecific antibody produced by recombinant CHO cells

Wook-Dong Kim, Miwako Tokunaga, Hiroyuki Ozaki, Takuya Ishibashi, Kohsuke Honda, Hiroyuki Kajiura, Kazuhito Fujiyama, Ryutaro Asano, Izumi Kumagai, Takeshi Omasa, Hisao Ohtake

Journal:

Applied Microbiology and Biotechnology

Year:

2010

Language:

english

File:

PDF, 300 KB

english, 2010

44

Enhanced antibody production following intermediate addition based on flux analysis in mammalian cell continuous culture

Takeshi Omasa, Keisuke Furuichi, Tomoya Iemura, Yoshio Katakura, Michimasa Kishimoto, Ken-ichi Suga

Journal:

Bioprocess and Biosystems Engineering

Year:

2010

Language:

english

File:

PDF, 383 KB

english, 2010

45

Integrated biooxidation and acid dehydration process for monohydroxylation of aromatics

Shiho Yamashita, Yuka Sameshima, Masaaki Konishi, Junichi Kato, Michimasa Kishimoto, Kohsuke Honda, Takeshi Omasa, Hisao Ohtake

Journal:

Process Biochemistry

Year:

2007

Language:

english

File:

PDF, 486 KB

english, 2007

46

Amplified Gene Location in Chromosomal DNA Affected Recombinant Protein Production and Stability of Amplified Genes

Tomohiro Yoshikawa, Fumi Nakanishi, Yuki Ogura, Daisuke Oi, Takeshi Omasa, Yoshio Katakura, Michimasa Kishimoto, Ken-ichi Suga

Journal:

Biotechnology Progress

Year:

2000

Language:

english

File:

PDF, 175 KB

english, 2000

47

Construction and Evaluation of Drug-Metabolizing Cell Line for Bioartificial Liver Support System

Takeshi Omasa, Kazumi Kim, Shinya Hiramatsu, Yoshio Katakura, Michimasa Kishimoto, Shin Enosawa, Hisao Ohtake

Journal:

Biotechnology Progress

Year:

2005

Language:

english

File:

PDF, 143 KB

english, 2005

48

Evaluation of stable and highly productive gene amplified CHO cell line based on the location of amplified genes

Tomohiro Yoshikawa, Fumi Nakanishi, Seima Itami, Daisuke Kameoka, Takeshi Omasa, Yoshio Katakura, Michimasa Kishimoto, Ken-ichi Suga

Journal:

Year:

2000

Language:

english

File:

PDF, 174 KB

english, 2000

49

Construction of BAC-based physical map and analysis of chromosome rearrangement in chinese hamster ovary cell lines

Yihua Cao, Shuichi Kimura, Takayuki Itoi, Kohsuke Honda, Hisao Ohtake, Takeshi Omasa

Journal:

Biotechnology and Bioengineering

Year:

2012

Language:

english

File:

PDF, 591 KB

english, 2012

50

Enhancement of sialylation on humanized IgG-like bispecific antibody by overexpression of α2,6-sialyltransferase derived from Chinese hamster ovary cells

Masayoshi Onitsuka, Wook-Dong Kim, Hiroyuki Ozaki, Akira Kawaguchi, Kohsuke Honda, Hiroyuki Kajiura, Kazuhito Fujiyama, Ryutaro Asano, Izumi Kumagai, Hisao Ohtake, Takeshi Omasa

Journal:

Applied Microbiology and Biotechnology

Year:

2012

Language:

english

File:

PDF, 592 KB

english, 2012